Detail for CD133high CSCs


Full Name

CD133-high Cancer Stem Cells

Gene Name

Not Detected

Related Disease

  • Pancreatic Cancer [ref.1]
  • Hepatic Cancer [ref.1]

Function

CD133 antigen is a glycoprotein that in humans is encoded by the PROM1 gene. It is a member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localize to cellular protrusions. CD133 is a common marker of cancer stem cells (CSCs). 

Reference

  • [1] Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo.
    Huang, J., et al. (2013). Clin Immunol 149(1): 156-168. [ 23994769 ]

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