Drug name: pLenti6.3/V5-DEST Gateway Vector


Related CSCTT Targets

microRNA 143 [ref.1]

Introduction

The pLenti6.3/V5-DEST Gateway Vector is a Gateway-adapted ViraPower lentiviral expression vector for lentiviral-based expression of a target gene in dividing and non-dividing mammalian cells. The vector is equipped with two key genetic elements, making it a HiPerform vector: the Woodchuck Posttranscriptional Regulatory Element (WPRE) and the central Polypurine Tract (cPPT) sequence from the HIV-1 integrase gene to produce at least 4-fold increase in protein expression compared to vectors lacking these elements.

Schema

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Reference

  • [1] miR-143 inhibits glycolysis and depletes stemness of glioblastoma stem-like cells.
    Zhao, S., et al. (2013). Cancer Lett 333(2): 253-260. [ 23376635 ]

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