Detail for CD138-/CD34- cells


Full Name

CD138-/CD34- stem cells

Gene Name

Not Detected

Related Disease

  • Multiple Myeloma [ref.1]

Function

CD138-/CD34- cells may actually be tumor stem cells responsible for initiation and relapse of multiple myeloma. However, effective drugs targeted at CD138-/CD34- tumor stem cells are yet to be developed. PTX-NPs proved to be a potent anticancer treatment strategy that may contribute to targeted therapy for multiple myeloma tumor stem cells in future clinical trials.

Related Pathway/CSCs feature

  • Not Detected

Reference

  • [1] Paclitaxel-Fe3O4 nanoparticles inhibit growth of CD138(-) CD34(-) tumor stem-like cells in multiple myeloma-bearing mice.
    Yang, C., et al. (2013). Int J Nanomedicine 8: 1439-1449.. [ 23610522 ]

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